Multi-Site Studies for System-Level Implementation of Substance Use Prevention and Treatment Services (R01)

PAR-16-455
Multi-Site Studies for System-Level Implementation of Substance Use Prevention and Treatment Services (R01)
Department of Health and Human Services
National Institutes of Health

Section I. Funding Opportunity DescriptionRx-Drugs

Implementation science is a growing field. An early area of emphasis for addiction health services researchers was to move beyond training of individual clinicians or service providers as a default implementation strategy, and develop interventions that would achieve broader, sustainable implementation at the organizational level. Some research has begun to look at intra-organizational implementation strategies to further accelerate the implementation of evidence-based practices (or de-implementation of unsupported or harmful practices). However, to date, a major remaining challenge is how to facilitate – in a systematic, scalable, sustainable way – the delivery of evidence-based prevention and treatment services at a system level.

This FOA seeks research projects that will move beyond a focus on how individual clinics or organizations implement a given change, and beyond implementation of interventions that target only a single evidence-based intervention (EBI). The purpose of this FOA is to identify efficacious and effective strategies or techniques for facilitating systems-level change within or across networks of organizations to promote broad use of evidence-based practices for the prevention and/or treatment of substance use disorders or HIV. This FOA seeks applications that can address implementation on a larger, system-level scale that is more analogous to the way policy changes lead to system-level changes in prevention and treatment service delivery. Achieving system-level improvements requires implementation strategies that are sufficiently flexible to address the variation in settings and context across a given system, but that are also generalizable across settings. The multi-site studies supported by this FOA should contribute both practical and conceptual advances.  In practical terms, these studies should provide strategies that can be used to effectively deploy guidelines, practices, and policies across entire systems of care.  In conceptual terms, these studies should also leverage the multi-site platform to test implementation science hypotheses, explore novel methodological approaches, or test new measures or models that can inform future implementation research in this or other health domains.

General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-16-455
Funding Opportunity Title: Multi-Site Studies for System-Level Implementation of Substance Use Prevention and Treatment Services (R01)
Opportunity Category: Discretionary
Opportunity Category Explanation:  
Funding Instrument Type: Grant
Category of Funding Activity: Education
Health
Category Explanation:  
Expected Number of Awards:  
CFDA Number(s): 93.273 — Alcohol Research Programs
93.279 — Drug Abuse and Addiction Research Programs
93.399 — Cancer Control
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Sep 30, 2016
Last Updated Date: Sep 30, 2016
Original Closing Date for Applications: Nov 13, 2020  
Current Closing Date for Applications: Nov 13, 2020  
Archive Date: Dec 14, 2020
Estimated Total Program Funding:  
Award Ceiling: $500,000
Award Floor:

Eligibility

Eligible Applicants: Public housing authorities/Indian housing authorities
City or township governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Independent school districts
Public and State controlled institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
County governments
Private institutions of higher education
Native American tribal governments (Federally recognized)
Special district governments
Small businesses
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Additional Information

Agency Name: National Institutes of Health
Description: As part of the Collaborative Research on Addiction at NIH (CRAN) initiative, NIDA, NIAAA, and NCI join to issue this FOA. The purpose of this FOA is to support the development and testing of interventions, models, and/or frameworks that examine system-level implementation of evidence-based interventions, guidelines, or principles to improve the delivery, uptake, quality, and sustainability of substance use prevention and treatment interventions and services.
Link to Additional Information: http://grants.nih.gov/grants/guide/pa-files/PAR-16-455.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV

If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

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BRAIN Initiative: Data Archives for the BRAIN Initiative (R24)

RFA-MH-17-255
BRAIN Initiative: Data Archives for the BRAIN Initiative (R24)
Department of Health and Human Services
National Institutes of Health

Section I. Funding Opportunity Descriptionbrain
Background

The BRAIN Initiative: The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative® is aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a new dynamic picture of the brain that, for the first time, will show how individual cells and complex neural circuits interact in both time and space. It is expected that the application of these new tools and technologies will ultimately lead to new ways to treat and prevent brain disorders.

NIH is one of several federal agencies involved in the BRAIN Initiative. Planning for the NIH component of the BRAIN initiative is guided by the long-term scientific plan, “BRAIN 2025: A Scientific Vision,” which details seven high-priority research areas and calls for a sustained federal commitment of $4.5 billion over 12 years. This FOA and other FOAs issued in Fiscal Year 2017 are based on careful consideration by the NIH of the recommendations of the BRAIN 2025 Report, and input from the NIH BRAIN Multi-Council Working Group.  Videocasts of the NIH BRAIN Multi-council Working Group are available at http://www.braininitiative.nih.gov/about/mcwg.htm.

To enable rapid progress in development of new technologies as well as in theory and data analysis, the BRAIN Initiative encourages collaborations between neurobiologists and scientists from statistics, physics, mathematics, engineering, and computer and information sciences; and NIH welcomes applications from investigators in these disciplines.

NIH encourages BRAIN Initiative applications from investigators that are underrepresented in the biomedical, behavioral, or clinical research workforce (see data athttp://www.nsf.gov/statistics/showpub.cfm?TopID=2&SubID=27 and the most recent report on Women, Minorities, and Persons with Disabilities in Science and Engineering). Such individuals include those from underrepresented racial and ethnic groups, those with disabilities, and those from disadvantaged backgrounds.

NIH also encourages businesses to participate in the BRAIN Initiative.  It is possible for companies to submit applications directly to BRAIN Initiative program announcements or to collaborate with academic researchers in joint submissions.  Small businesses should consider applying to one of the BRAIN Initiative small business FOAs (http://braininitiative.nih.gov/funding/index.htm).

In addition to the National BRAIN initiative, the NIH continues to have a substantial annual investment in neuroscience research. The Institutes and Centers contributing to the NIH BRAIN Initiative (http://braininitiative.nih.gov/ ) support those research efforts through investigator-initiated applications as well as through specific FOAs. Potential applicants to this FOA are strongly encouraged to contact Scientific/Research staff if they have any questions about the best FOA for their research.

The BRAIN Initiative will require a high level of coordination and sharing between investigators. It is expected that BRAIN Initiative awardees will cooperate and coordinate their activities after awards are made by participating in Program Director/Principal Investigator (PD/PI) meetings and in other activities.

This FOA is related to the recommendations in Section III.5 of the BRAIN 2025 Report.  Specifically, this FOA solicits applications that will address the recommendations on “Identifying Fundamental Principles”.

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-MH-17-255
Funding Opportunity Title: BRAIN Initiative: Data Archives for the BRAIN Initiative (R24)
Opportunity Category: Discretionary
Opportunity Category Explanation:  
Funding Instrument Type: Grant
Category of Funding Activity: Education
Health
Income Security and Social Services
Category Explanation:  
Expected Number of Awards:  
CFDA Number(s): 93.173 — Research Related to Deafness and Communication Disorders
93.213 — Research and Training in Complementary and Integrative Health
93.242 — Mental Health Research Grants
93.273 — Alcohol Research Programs
93.279 — Drug Abuse and Addiction Research Programs
93.286 — Discovery and Applied Research for Technological Innovations to Improve Human Health
93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders
93.865 — Child Health and Human Development Extramural Research
93.866 — Aging Research
93.867 — Vision Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Sep 21, 2016
Last Updated Date: Sep 21, 2016
Original Closing Date for Applications: Oct 19, 2017  
Current Closing Date for Applications: Oct 19, 2017  
Archive Date: Nov 19, 2017
Estimated Total Program Funding:  
Award Ceiling:  
Award Floor:

Eligibility

Eligible Applicants: For profit organizations other than small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
County governments
Independent school districts
Special district governments
Public housing authorities/Indian housing authorities
Small businesses
Private institutions of higher education
City or township governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Native American tribal governments (Federally recognized)
Public and State controlled institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: This Funding Opportunity Announcement (FOA) solicits applications to develop web-accessible data archives to capture, store, and curate data related to BRAIN Initiative activities. The data archives will work with the research community to incorporate tools that allow users to analyze and visualize the data, but the creation of such tools is not part of this FOA. The data archives will use appropriate standards to describe the data, but the creation of such standards is not part of this FOA. A goal of this program is to advance research by creating a community resource data archive with appropriate standards and summary information that is broadly available and accessible to the research community for furthering research.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-17-255.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV

If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit-Specific Processes in the Brain (R01)

RFA-MH-17-220
BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit-Specific Processes in the Brain (R01)
Department of Health and Human Services
National Institutes of Health

neuron

Research Objectives

This funding opportunity announcement (FOA) is designed to support development and validation of novel tools to facilitate the detailed analysis of cells and circuits and provide insights into the neural circuitry and structure underlying complex behaviors. The human brain consists of an estimated one hundred billion neurons and more than one trillion supporting glial cells that are uniquely organized to confer the extraordinary computational activities of the brain. Cell types are categorized by their anatomical position, neurotransmitter content, dendritic and axonal connections, receptor profile, gene expression profile and distinct electrical properties. Although the human brain has long been the focus of numerous studies with many major achievements along the way, to date we remain largely ignorant about the specific details such as cell types and connections that are responsible for rapid information processing. Defining cellular and circuit-level function is dependent on detailed knowledge about the components and structure of the circuit. Such knowledge, in turn, is fundamental to understanding how these features underlie cognition and behavior, which should aid in the development of targeted cell-type and circuit-specific therapeutics to treat brain disorders. This initiative is focused on developing tools (or vastly improving existing tools) to enable access to individual cells and defined groups of cells within neuronal circuits. The tools sought through this FOA can include novel genetic or non-genetic methods for targeted delivery of genes, proteins, and chemicals to specific cells or tightly defined cell types and circuits.

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-MH-17-220
Funding Opportunity Title: BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit-Specific Processes in the Brain (R01)
Opportunity Category: Discretionary
Opportunity Category Explanation:  
Funding Instrument Type: Grant
Category of Funding Activity: Education
Health
Income Security and Social Services
Category Explanation:  
Expected Number of Awards:  
CFDA Number(s): 93.173 — Research Related to Deafness and Communication Disorders
93.213 — Research and Training in Complementary and Integrative Health
93.242 — Mental Health Research Grants
93.273 — Alcohol Research Programs
93.279 — Drug Abuse and Addiction Research Programs
93.286 — Discovery and Applied Research for Technological Innovations to Improve Human Health
93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders
93.865 — Child Health and Human Development Extramural Research
93.866 — Aging Research
93.867 — Vision Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Aug 10, 2016
Last Updated Date: Sep 16, 2016
Original Closing Date for Applications: Nov 02, 2016  
Current Closing Date for Applications: Oct 13, 2017  
Archive Date: Nov 12, 2017
Estimated Total Program Funding:  
Award Ceiling:  
Award Floor:  

Eligibility

Eligible Applicants: Private institutions of higher education
State governments
Special district governments
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
County governments
Small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Independent school districts
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled “Additional Information on Eligibility” for clarification)
City or township governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
Public housing authorities/Indian housing authorities
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application. The development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest or approaches that are expected to target specific cell types and/or circuits in the nervous system with greater precision and sensitivity than currently established methods are encouraged. Tools that can be used in a number of species/model organisms rather than those restricted to a single species are highly desired. Applications that provide approaches that break through existing technical barriers to substantially improve current capabilities are highly encouraged.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-17-220.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV

If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

Bold New Bioengineering Methods and Approaches for Heart, Lung, Blood and Sleep Disorders and Diseases (R21)

RFA-HL-17-015
Bold New Bioengineering Methods and Approaches for Heart, Lung, Blood and Sleep Disorders and Diseases (R21)
Department of Health and Human Services
National Institutes of Healthnew lungs

Purpose

The purpose of this funding opportunity announcement (FOA) is to seek innovative, high-risk bioengineering research for which preliminary results have not yet been obtained, explore new approaches or concepts that are important to a substantive heart, lung, blood or sleep disorder or disease, support the translation of research into practice, technologies, or commercial products, and to develop trans-disciplinary projects upon which significant future research may be built.  This  program will allow investigators to enter new fields and apply cutting-edge approaches to improve the Nation’s health through bioengineering research.  In particular, ground-breaking studies aimed towards the development of novel agents, materials or coatings related to medical devices and engineered tissues would be uniquely fostered by this FOA.

Background

Originally conceptualized by the NIH Bioengineering Consortium in 2003, NHLBI Exploratory Bioengineering Research Grants (EBRGs) were submitted under PA-12-284 (reissued as PA-16-040, which is administered by NIBIB).  NHLBI examined its EBRG R21 portfolio and found this funding mechanism as a useful and cost-effective way for established investigators to open new areas of research. Our data suggests that low-cost, short term projects may incentivize research teams, especially those not captured by the traditional R01 mechanism.

Why Bioengineering? The NHLBI bioengineering community has transformed medicine by creating the artificial heart, pacemakers and Implantable Cardioverter Defibrillators, Ventricular Assist Devices, stents, human tissue chip devices and cell/gene/combination product therapies. These examples demonstrate that bioengineering is a synergistic approach that crosses not only all technology-related areas of NHLBI, but also all of our Disease-specific domains. Further, bioengineering is unique because unlike most scientific focuses, such as heart disease, it demands collaboration across disciplines, which looks to be necessary for advancement of needed technologies. Our ability to achieve alternative and more effective therapies is an urgent need for NHLBI. It is envisioned that this targeted RFA will serve as an opportunity to address scientific gaps and to programmatically balance bioengineering projects across the NHLBI. We are seeking only the most unique, highly innovative and groundbreaking approaches with potential for significant impact on reducing the burden of disease. Applicants are advised to query NIH RePORTER to make sure their approach or idea has not been funded before.

The use of the R21 mechanism is intended to support short-term exploratory research projects. Long-term projects, or projects designed to increase knowledge in a well-established area, will not be considered for R21 awards. Additionally, R21 applications may involve considerable risk, so they should clearly explain the significance of the proposed work and why the potential impact outweighs these risks

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-HL-17-015
Funding Opportunity Title: Bold New Bioengineering Methods and Approaches for Heart, Lung, Blood and Sleep Disorders and Diseases (R21)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards:
CFDA Number(s): 93.233 — National Center on Sleep Disorders Research
93.837 — Cardiovascular Diseases Research
93.838 — Lung Diseases Research
93.839 — Blood Diseases and Resources Research
93.840 — Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
Cost Sharing or Matching Requirement: No
Posted Date: Jun 13, 2016
Last Updated Date: Jun 13, 2016
Original Closing Date for Applications: May 10, 2019  
Current Closing Date for Applications: May 10, 2019  
Archive Date: Jun 10, 2019
Estimated Total Program Funding: $1,350,000
Award Ceiling: $150,000

Eligibility

Eligible Applicants:
For profit organizations other than small businesses
Special district governments
County governments
City or township governments
State governments
Public and State controlled institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Public housing authorities/Indian housing authorities
Small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Native American tribal governments (Federally recognized)
Private institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name: National Institutes of Health
Description: The purpose of this Funding Opportunity Announcement (FOA) is to encourage basic, translational, and clinical proof-of-concept research projects that are needed for the advancement of bioengineering approaches for heart, lung, blood and sleep diseases.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-17-015.html
Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

Methodology and Measurement in the Behavioral and Social Sciences (R01)

PAR-16-260
Methodology and Measurement in the Behavioral and Social Sciences (R01)
Department of Health and Human Services
National Institutes of Health

Scintific_Methods

Purpose

The behavioral and social sciences offer significant fundamental insights into the comprehensive understanding of human health, including disease etiology, prevention, treatment, and the promotion of health and well-being. To advance the investigation of behavioral and social factors in health and disease, and enhance the rigor and reproducibility of study results, the participating Institutes and Centers (ICs) invite qualified researchers to submit research grant applications on methodology and measurement in the behavioral and social sciences relevant to the missions of the NIH ICs.

Background

Methodology encompasses research design, measurement, data collection, and data analysis techniques. Research design addresses selection of appropriate study designs, inclusion/exclusion criteria, sampling plan, study subject protections, participant engagement and recruitment, and procedures and measures to accomplish the research goals and ensure internal and external validity. Measurement addresses the quantification and characterization of study variables relevant to the research hypotheses, in a manner that maximizes the validity, reliability, and utility of the data.  Data collection techniques are the tools and procedures for acquiring, integrating and curating data from a wide range of sources, such as self-reports, geocoded mobile devices, sensors, biomarker assay platforms, and complex large-scale datasets. Analytic methods address the conceptual and technical aspects of analyzing, interpreting and reporting data to improve hypothesis testing and prediction. Advancement of methodologic research in design, measurement, data collection and data analysis will enhance the quality and power of human and animal data in health-related behavioral and social science.

Research Objectives

Applicants are encouraged but not required to address methodologic issues related to:

  • interdisciplinary, multimethod, and multilevel approaches in behavioral and social science research, including broadly applicable approaches that foster integration with biomedical, physical, or computational science research or engineering.
  • Integrating, mining and modeling behavioral and social science data in combination with genetic, epigenetic, biomarker and imaging data.
  • research in diverse populations that are distinctive by virtue of demographics, cultural or linguistic characteristics, sexual orientation or gender identity, health system, mental or physical abilities, underrepresentation in research or other factors, where the outcome would have a significant impact on improving health in that population.
  • the study of sensitive health-related behaviors in the context of healthcare, the social environment, and local/state/national policies.
  • ethics in research, such as informed consent, enrollment of minors including assent, assessment of risk and benefit, selection and retention of participants, privacy and confidentiality.

General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-16-260
Funding Opportunity Title: Methodology and Measurement in the Behavioral and Social Sciences (R01)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Education
Health
Category Explanation:
Expected Number of Awards:
CFDA Number(s): 93.173 — Research Related to Deafness and Communication Disorders
93.213 — Research and Training in Complementary and Integrative Health
93.273 — Alcohol Research Programs
93.313 — NIH Office of Research on Women’s Health
93.393 — Cancer Cause and Prevention Research
93.399 — Cancer Control
93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders
93.866 — Aging Research
93.867 — Vision Research
Cost Sharing or Matching Requirement: No
Posted Date: May 16, 2016
Last Updated Date: May 16, 2016
Original Closing Date for Applications: Sep 07, 2019  
Current Closing Date for Applications: Sep 07, 2019  
Archive Date: Oct 08, 2019
Estimated Total Program Funding:  Not Listed
Award Ceiling:  Not Listed
Award Floor:

Eligibility

Eligible Applicants:
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
For profit organizations other than small businesses
City or township governments
Public and State controlled institutions of higher education
Independent school districts
County governments
Special district governments
State governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Public housing authorities/Indian housing authorities
Native American tribal governments (Federally recognized)
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Private institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: The purpose of this Funding Opportunity Announcement (FOA) is to invite qualified researchers to submit grant applications aimed at improving and developing methodology in the behavioral and social sciences through innovations in research design, measurement, data collection and data analysis techniques.
Link to Additional Information: http://grants.nih.gov/grants/guide/pa-files/PAR-16-260.html
Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

For Information on the R21 associated with this grant please click the following link:
http://www.grants.gov/web/grants/view-opportunity.html?oppId=283874

Adult Maturational Changes and Dysfunctions in Emotion Regulation (R01)

RFA-MH-17-405
Adult Maturational Changes and Dysfunctions in Emotion Regulation (R01)
Department of Health and Human Services
National Institutes of Health

brain

Background

Research suggests that, for many adults, normal aging is associated with general trends toward improved emotion regulation (e.g., as evidenced by increasing positive and decreasing negative affect, greater emotional stability, higher life satisfaction, a “positivity effect” in information-processing).  As compared with younger adults, older adults often show superior emotion regulation capacities, employ different strategies for executive control of emotional information, and recruit different neural networks in performing affective tasks.  Such patterns have been variously hypothesized to stem from increased motivation to maintain emotional well-being, learning of more skillful and efficient emotion processing strategies, or compensatory adaptations to age-related brain changes. A number of hypotheses regarding the strategies older adults employ to regulate emotion and the neurobiological systems that support them remain untested.  There is also considerable evidence that men and women process emotions differently, though, to date, evidence is scarce regarding whether and how sex differences may be modulated during the aging process.

Not all adults demonstrate the positive emotion regulation profiles that characterize adaptive aging.  To date, there has been little mechanistic research focused on sources of individual variability in development and maturation of emotional regulatory functions. Mood and anxiety disorders are considered examples of affect dysregulation.  However, knowledge tends to be limited about the specific emotion processing deficits involved, and how these may change with maturation.  Few studies employing affective neuroscience methods have examined adult maturational processes relative to mental disorder.  There has been little scientific investigation of the extent to which adults with affective disorders manifest or fail to show the normative maturational shifts, or at what point(s) during the adult lifespan they may tend to traverse divergent emotion regulation trajectories.

In addition, significant gaps remain in our understanding of successful emotion regulation in adults aging without mental disorders.  It is paradoxical that, despite normative cognitive declines with age, many aspects of emotional function improve with age.  Though attributed to improved emotional regulatory strategies, such strategies frequently rely on the same cognitive control capacities that decline with aging.  Numerous questions remain regarding the role of cognitive control in adaptive emotional aging, alternative strategies that older adults might employ to regulate emotion, the cognitive processes that undergird those strategies, and the causes of individual variation in the ability to engage these strategies with advancing age.

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-MH-17-405
Funding Opportunity Title: Adult Maturational Changes and Dysfunctions in Emotion Regulation (R01)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards:
CFDA Number(s): 93.242 — Mental Health Research Grants
93.866 — Aging Research
Cost Sharing or Matching Requirement: No
Posted Date: Mar 29, 2016
Last Updated Date: Mar 29, 2016
Original Closing Date for Applications: Jul 22, 2016  
Current Closing Date for Applications: Jul 22, 2016  
Archive Date: Aug 22, 2016
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants:
State governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
Independent school districts
For profit organizations other than small businesses
Public and State controlled institutions of higher education
Private institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Special district governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled “Additional Information on Eligibility” for clarification)
County governments
Native American tribal organizations (other than Federally recognized tribal governments)
City or township governments
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: This funding opportunity announcement (FOA) invites applications for mechanistic research on how age- and sex-related changes in emotion processing develop over the adult life course and how these changes may interact with and inform the understanding of affective dysregulation in adult mental disorders and Alzheimer’s disease.In particular, research is sought that will leverage the already established normative backdrop of generally improved emotion regulation with aging, as well as research that will expand this evidence base.One aim is to clarify the trajectories of change in emotion processing and linked neurobiological and neurobehavioral factors in aging adults who experience mood and anxiety disorders.Equally important aims are to advance understanding of the factors involved in normative maturational shifts in these processes and of sources of individual variation therein, and to clarify how such shifts (or lack thereof) may relate to irregularities in the integrative neural-behavioral mechanisms of affect regulation seen in these adult mental disorders and in Alzheimer’s disease.It is anticipated that such studies may identify novel targets for mental health interventions or prevention efforts, or provide clues as to which available intervention strategies might be optimally applied to normalize emotion dysregulation or to strengthen emotional resilience at particular stages of the adult life cycle.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-17-405.html
Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

The Application of Big Data Analytics to Drug Abuse Research (R01)

PA-16-119
The Application of Big Data Analytics to Drug Abuse Research (R01)
Department of Health and Human ServicesRx-Drugs
National Institutes of Health

Nature of the Research Opportunity

Big Data is used here to refer to computational analytic techniques able to recognize patterns in information which surpass the limits of human intuition.  This FOA focuses on applying Big Data analytics to reveal deeper or novel insights into the biological and behavioral processes associated with substance abuse and its treatment, and the relationships among them.   This FOA does not seek applications that propose to perform secondary analyses of data without using Big Data analytics (e.g. this FOA does not seek applications re-applying traditional methods to ascertain un-analyzed distinctions between study subpopulations) and applicants may consider submitting these applications to PA-13-080.  This FOA also is intended to distinguish itself from PA-13-080 in that the computational tools (e.g. aggregated datasets, standards, analytic software) developed to answer new scientific questions are able to be applied again to future research studies acquiring similar types of data, such that the end result of these funded grants increase the computational armamentarium available to addiction research.

Background

National investments in basic research, including President Obama’s BRAIN and Precision Medicine Initiatives, are poised to accelerate discoveries in neuroscience, genetics, and health services research.  In addition, a shift in culture, driven by the NIH Big Data to Knowledge Initiative, is promoting open access and data sharing to allow diverse data sets to be broadly accessible to researchers. Advances in information technologies and analytics capabilities are producing extraordinary capacity to integrate and analyze these data and enable novel research into the complexity of disorders such as drug abuse and addiction that are driven by the dynamic interactions of diverse biological, social, organizational, environmental, and behavioral mediators.   The result is a new, data-intensive era of research characterized by a heretofore unseen influx of data presenting new computational challenges which delay important discoveries due to bottlenecks in data analysis.  Big Data analytics provides new opportunities to maximize the value of research results by providing researchers the ability to analyze huge amounts of data in new ways – turning vast datasets of complex information into knowledge.

General Information

Document Type: Grants Notice
Funding Opportunity Number: PA-16-119
Funding Opportunity Title: The Application of Big Data Analytics to Drug Abuse Research (R01)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Education
Health
Category Explanation:
Expected Number of Awards:
CFDA Number(s): 93.279 — Drug Abuse and Addiction Research Programs
Cost Sharing or Matching Requirement: No
Posted Date: Mar 09, 2016
Last Updated Date: Mar 09, 2016
Original Closing Date for Applications: May 07, 2019  
Current Closing Date for Applications: May 07, 2019  
Archive Date: Jun 07, 2019
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants:
Special district governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Public housing authorities/Indian housing authorities
For profit organizations other than small businesses
Independent school districts
Public and State controlled institutions of higher education
City or township governments
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Private institutions of higher education
Native American tribal governments (Federally recognized)
State governments
County governments
Small businesses
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: The purpose of this FOA is to encourage the application of Big Data analytics to reveal deeper or novel insights into the biological and behavioral processes associated with substance abuse and addiction.NIDA recognizes that to accelerate progress toward understanding how the human brain and behavior is altered by chronic drug use and addiction, it is vital to develop more powerful analytical methods and visualization tools that can help capture the richness of data being generated from genetic, epigenetic, molecular, proteomic, metabolomic, brain-imaging, micro-electrode, behavioral, clinical, social, services, environmental studies as well as data generated from electronic health records.Applications for this FOA should develop and/or utilize computational approaches for analyzing large, complex datasets acquired from drug addiction research.The rapid increase of technologies to acquire unprecedented amounts of neurobiological and behavioral data, and an expanding capacity to store those data, results in great opportunity to bring to bear the power of the computational methods of Big Data analytics on drug abuse and addiction.
Link to Additional Information: http://grants.nih.gov/grants/guide/pa-files/PA-16-119.html
Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster