FY17 DOD Joint Program Committee-2/Military Infectious Diseases Research Program (JPC-2/MIDRP)

Fiscal Year 2017 (FY17) funding opportunities for the Department of Defense (DOD) Joint Program Committee-2/Military Infectious Diseases Research Program (JPC-2/MIDRP) that are being managed by the office of Congressionally Directed Medical Research Programs (CDMRP).

Applied Research Award

SUBMISSION AND REVIEW DATES AND TIMES

• Pre-Application Deadline: 5:00 p.m. Eastern time (ET), January 25, 2016

• Invitation to Submit an Application: March 7, 2016

• Application Submission Deadline: 11:59 p.m. ET, May 9, 2016

• End of Application Verification Period: 5:00 p.m. ET, May 12, 2016

• Peer Review: July 2016

• Programmatic Review: August 2016

FY17 JPC-2/MIDRP Applied Research Award Focus Areas

To meet the intent of the FY17 JPC-2/MIDRP Applied Research Award (ARA) mechanism, applications MUST specifically address at least one of the FY17 JPC-2/MIDRP ARA Focus Areas related to combat-related or trauma-induced wound infections listed below. Research projects incorporating high-throughput drug screening and/or in silico modeling, as well as applications focused on areas other than those listed below will not be considered for funding.

FOCUS AREAS:

• Development of new methods for rapid multi-pathogen/multi-phenotype detection of multidrug-resistant organisms (MDROs), nosocomial pathogens, and/or rapid multipathogen/multi-phenotype characterization of antimicrobial resistance patterns.

• Development of assays for host immune response biomarkers for diagnosis or prognosis (with associated outcomes) of infection to inform clinical infection management decisions (e.g., optimal wound closure time, optimal duration of antibiotic administration for osteomyelitis).

• Development and preclinical testing of novel chemotypes (chemical classes/materials), biologics as potential therapeutics or prophylactics for wound infection, and/or biofilm formation, maintenance, or propagation. Innovative treatment approaches (e.g., chelators, antibody, phage, antimicrobial peptides, quorum-sensing inhibitors, and host immunoaugmentation, etc.) are encouraged.

APPLICABLE TO ALL FOCUS AREAS:

• Studies involving carbapenem-resistant organisms are particularly sought.

• Preference will be given to approaches that address infections with one or more MDROs, particularly, Acinetobacter baumannii, Pseudomonas aeruginosa, extendedspectrum beta-lactamase producing Enterobacteriaceae (including Escherichia coli and Klebsiella pneumoniae), and methicillin-resistant Staphylococcus aureus (MRSA), and/or invasive fungal (mold) pathogens.

• Preference will be given to studies leading toward topical treatments for prevention and management of wound infection.

Clinical Study Award

SUBMISSION AND REVIEW DATES AND TIMES

• Pre-Application Deadline: 5:00 p.m. Eastern time (ET), January 25, 2016

• Invitation to Submit an Application: March 7, 2016

• Application Submission Deadline: 11:59 p.m. ET, May 9, 2016

• End of Application Verification Period: 5:00 p.m. ET, May 12, 2016

• Peer Review: July 2016

• Programmatic Review: August 2016

FY17 JPC-2/MIDRP Clinical Study Award Focus Areas

To meet the intent of the FY17 JPC-2/MIDRP Clinical Study Award (CSA) mechanism, applications MUST contain only one clinical trial/testing with a distinct study design and address at least one of the Focus Areas listed below. Applications focused on areas other than those listed below will not be considered for funding.

FOCUS AREAS:

Therapeutics. Evaluation of optimum preventive or directive therapies for combatrelated or trauma-induced wound infections using Food and Drug Administration (FDA)-approved drugs, biologics, or devices either alone or in combination. Studies focusing on new indications of FDA-approved drugs/biologics/devices or investigational new drugs/biologics/devices will be accepted.

Rapid detection of pathogens and/or anti-microbial drug resistance markers. Evaluation of a functional prototype device or assay for the rapid detection of pathogens and/or anti-microbial drug resistance markers in combat-related or traumainduced wounds. Research outcomes should support the development of an FDA regulated device or assay.

  • Rapid detection of biomarkers. Evaluation of a functional prototype device or assay for the rapid detection of novel and specific in vivo or in vitro biomarkers (from wound, serum, saliva, or urine) that predict development of infection or discriminate between infection and colonization. Research outcomes should support the development of an FDA-regulated device or assay.

APPLICABLE TO ALL FOCUS AREAS:

• Studies involving carbapenem-resistant organisms are particularly sought.

• Preference will be given to approaches that address infections with one or more multidrug-resistant organisms (MDROs), particularly, Acinetobacter baumannii, Pseudomonas aeruginosa, extended-spectrum beta-lactamase producing Enterobacteriaceae (including Escherichia coli and Klebsiella pneumoniae), methicillin-resistant Staphylococcus aureus (MRSA), and/or invasive fungal (mold) pathogens.

Psychological Health/Traumatic Brain Injury Research Program – Comprehensive Universal Prevention/Health Promotion Interventions Award

Psychological Health/Traumatic Brain Injury Research Program

DoD PH/TBI Comprehensive Universal Prevention/Health Promotion Interventions AwardPsychological-Assessments-and-Counselling
Department of Defense
Dept. of the Army — USAMRAA

B. Award Description
The intent of the FY15 PH/TBI Comprehensive Universal Prevention/Health Promotion Interventions (CUP/HPI) Award is to support research focused on the development, adaptation, efficiency or optimization, and testing of comprehensive universal prevention/health promotion interventions and systems-level approaches for use within the military context. This Program Announcement/Funding Opportunity seeks research applications that are designed to have positive effects on multiple target behaviors and outcomes.

Research should address shared common antecedents or precursors and shared risk and protective factors and interventions that have an effect on multiple outcomes. Interventions and systems-level approaches should increase protective factors and positive outcomes and reduce risk factors and negative outcomes that are relevant to the needs of Service members, their families, and their communities. Applications should be limited to prevention interventions and systems-level approaches that are within the military’s legal and operational control. Examples of negative outcome targets of interest include, but are not limited to:
• Risky behaviors (e.g., substance use, misuse, and abuse [including alcohol, tobacco, and other substance use, non-medical use, misuse, and abuse of prescription drugs], aggressive and other unsafe driving, and health-risking sexual behaviors [HRSB] related to HIV/AIDS)
• Aggression/violence
• Sexual assault
• Suicidal ideation and behaviors
• Depression
• Anxiety
• Sleep

General Information

Document Type: Grants Notice
Funding Opportunity Number: W81XWH-15-PHTBIRP-CUPHPI
Funding Opportunity Title: DoD PH/TBI Comprehensive Universal Prevention/Health Promotion Interventions Award
Opportunity Category: Discretionary
Funding Instrument Type: Cooperative Agreement
Grant
Category of Funding Activity: Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards: 4
CFDA Number(s): 12.420 — Military Medical Research and Development
Cost Sharing or Matching Requirement: No
Posted Date: Sep 2, 2015
Creation Date: Sep 2, 2015
Original Closing Date for Applications: Jan 14, 2016  
Current Closing Date for Applications: Jan 14, 2016  
Archive Date: Feb 13, 2016
Estimated Total Program Funding: $7,500,000
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants:
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility:

Additional Information

Agency Name: Dept. of the Army — USAMRAA
Description: The intent of the FY15 PH/TBI Comprehensive Universal Prevention/Health Promotion Interventions (CUP/HPI) Award is to support research focused on the development, adaptation, efficiency or optimization, and testing of comprehensive universal prevention/health promotion interventions and systems-level approaches for use within the military context. This Program Announcement/Funding Opportunity seeks research applications that are designed to have positive effects on multiple target behaviors and outcomes.

Link to Additional Information: http://www.grants.gov/web/grants/view-opportunity.html?oppId=278830