Grants for Early Medical/Surgical Subspecialists’ Transition to Aging Research (GEMSSTAR) (R03)

RFA-AG-17-012
Grants for Early Medical/Surgical Subspecialists’ Transition to Aging Research (GEMSSTAR) (R03)
Department of Health and Human Services
National Institutes of Health

1920

Program Description

The goal of the Grants for Early Medical/Surgical Specialists’ Transition to Aging Research (GEMSSTAR) program is to promote future leaders in clinical aging research across the range of medical and surgical specialties. To accomplish this goal, NIA will provide two years of support for small research projects to physicians trained in medical or surgical specialties who seek to become clinician-scientists in aging-related aspects of their specialty. Eligible applicants include, but are not limited to, physicians in traditional medical or surgical specialties, anesthesiologists, emergency medicine physicians, family medicine practitioners, general internists, general surgeons, geriatricians, hospitalists, neurologists, obstetricians/gynecologists, palliative care physicians, physiatrists, and psychiatrists.

The GEMSSTAR program is intended to support an early career physician’s first independent research project in aging. The GEMSSTAR program also provides an opportunity for applicants with funding support in non-aging-related fields to refocus their research efforts on aging-related issues. Thus, as the goal of the GEMSSTAR program is to promote future leaders in research on aging within their respective medical and surgical specialties, we seek applicants who aspire to continue or shift their research focus to bridge their specialty and the science of aging.

Research projects responsive to this initiative will combine aging with specialty clinical areas to focus on questions relevant to aging and/or the aged. The application should emphasize an integration of gerontologic or geriatric research with the candidate’s clinical specialty. Research could involve pilot or feasibility studies, secondary analyses of existing data, development of research methodology, development of new research technology, or other similar approaches. Projects may span the breadth of scientific domains, including basic, translational, clinical, genetic, or epidemiologic science. Human subjects, animal models, and in vitro systems are all acceptable as appropriate to the research questions. Projects should be appropriate to the background and level of experience of the applicant. Potential research topics may include, but are not limited to:

  • Characterization of an aging-related disease, condition, syndrome, or phenomenon relevant to a clinical specialty
  • Pilot investigation of a specialty-related intervention in older adults
  • Elucidation of mechanisms underlying specialty-related diseases in older age
  • Identification of predictors and/or outcomes of specialty-related interventions specific to older populations
  • Development of strategies to address and/or integrate important complexities common in older patients including multiple chronic conditions, polypharmacy, palliative care, multispecialty guideline integration, and/or preservation of function, cognition and independence for patients within one’s clinical specialty.
  • Multidisciplinary care strategies, including transitions across care settings, to improve outcome in older patients

To maximize the likelihood of an early-career physician to successfully complete the R03 research project, the GEMSSTAR program strongly encourages applicants to complement their R03 project with an additional concurrent and individualized professional development plan. Such a plan would augment an applicant’s specialty skills and knowledge with individualized aging/geriatrics research skills and knowledge, and cross-disciplinary collaboration.  Any complementary professional development plan would be supported by separate applicant-secured funding and would be independent of the R03 research plan and funding.

NIA supports a number of Centers and similar programs through which candidates may receive support for professional development activities complementary to the R03 award. Also a number of professional societies have indicated that they have funds available to support candidates in those specialties. A non-complete list of such resources includes:

It is expected that applicants will have expertise in their clinical specialty, but may be less experienced in geriatric or gerontologic science or other areas. As such, applications should include the participation of a senior collaborator with complementary expertise in aging-related research and, if needed, other collaborators and/or consultants in other areas appropriate to the proposed project. Applicants with a strong geriatrics background (such as geriatricians) who propose a research project that integrates their geriatrics expertise with a specific clinical problem embraced by a specialty should involve a senior collaborator with expertise in that clinical problem as it relates to older patients.

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-AG-17-012
Funding Opportunity Title: Grants for Early Medical/Surgical Subspecialists’ Transition to Aging Research (GEMSSTAR) (R03)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 15
CFDA Number(s): 93.866 — Aging Research
Cost Sharing or Matching Requirement: No
Posted Date: May 11, 2016
Last Updated Date: May 11, 2016
Original Closing Date for Applications: Oct 06, 2016  
Current Closing Date for Applications: Oct 06, 2016  
Archive Date: Nov 06, 2016
Estimated Total Program Funding: $1,700,000
Award Ceiling: $75,000

Eligibility

Eligible Applicants:
Special district governments
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Others (see text field entitled “Additional Information on Eligibility” for clarification)
For profit organizations other than small businesses
Public and State controlled institutions of higher education
Small businesses
State governments
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
City or township governments
Private institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Additional Information

Agency Name: National Institutes of Health
Description: The goal of the GEMSSTAR FOA is to provide support for early-stage physician-scientists, trained in medical or surgical specialties, to launch careers as future leaders in research on aging or in geriatrics. To achieve this goal, the GEMSSTAR FOA provides small grants to conduct transdisciplinary research on aging or in geriatrics research that will yield pilot data for subsequent aging- or geriatrics-focused research projects. As part of its focus on facilitating the development of early-stage physician-scientists who will become leaders in research on aging or in geriatrics, the GEMSSTAR FOA seeks to encourage the provision of supportive environments for candidates, and NIA will consider the extent to which a supportive environment is available to candidates in selecting GEMSSTAR candidates.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-17-012.html
Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

Adult Maturational Changes and Dysfunctions in Emotion Regulation (R01)

RFA-MH-17-405
Adult Maturational Changes and Dysfunctions in Emotion Regulation (R01)
Department of Health and Human Services
National Institutes of Health

brain

Background

Research suggests that, for many adults, normal aging is associated with general trends toward improved emotion regulation (e.g., as evidenced by increasing positive and decreasing negative affect, greater emotional stability, higher life satisfaction, a “positivity effect” in information-processing).  As compared with younger adults, older adults often show superior emotion regulation capacities, employ different strategies for executive control of emotional information, and recruit different neural networks in performing affective tasks.  Such patterns have been variously hypothesized to stem from increased motivation to maintain emotional well-being, learning of more skillful and efficient emotion processing strategies, or compensatory adaptations to age-related brain changes. A number of hypotheses regarding the strategies older adults employ to regulate emotion and the neurobiological systems that support them remain untested.  There is also considerable evidence that men and women process emotions differently, though, to date, evidence is scarce regarding whether and how sex differences may be modulated during the aging process.

Not all adults demonstrate the positive emotion regulation profiles that characterize adaptive aging.  To date, there has been little mechanistic research focused on sources of individual variability in development and maturation of emotional regulatory functions. Mood and anxiety disorders are considered examples of affect dysregulation.  However, knowledge tends to be limited about the specific emotion processing deficits involved, and how these may change with maturation.  Few studies employing affective neuroscience methods have examined adult maturational processes relative to mental disorder.  There has been little scientific investigation of the extent to which adults with affective disorders manifest or fail to show the normative maturational shifts, or at what point(s) during the adult lifespan they may tend to traverse divergent emotion regulation trajectories.

In addition, significant gaps remain in our understanding of successful emotion regulation in adults aging without mental disorders.  It is paradoxical that, despite normative cognitive declines with age, many aspects of emotional function improve with age.  Though attributed to improved emotional regulatory strategies, such strategies frequently rely on the same cognitive control capacities that decline with aging.  Numerous questions remain regarding the role of cognitive control in adaptive emotional aging, alternative strategies that older adults might employ to regulate emotion, the cognitive processes that undergird those strategies, and the causes of individual variation in the ability to engage these strategies with advancing age.

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-MH-17-405
Funding Opportunity Title: Adult Maturational Changes and Dysfunctions in Emotion Regulation (R01)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards:
CFDA Number(s): 93.242 — Mental Health Research Grants
93.866 — Aging Research
Cost Sharing or Matching Requirement: No
Posted Date: Mar 29, 2016
Last Updated Date: Mar 29, 2016
Original Closing Date for Applications: Jul 22, 2016  
Current Closing Date for Applications: Jul 22, 2016  
Archive Date: Aug 22, 2016
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants:
State governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
Independent school districts
For profit organizations other than small businesses
Public and State controlled institutions of higher education
Private institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Special district governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled “Additional Information on Eligibility” for clarification)
County governments
Native American tribal organizations (other than Federally recognized tribal governments)
City or township governments
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: This funding opportunity announcement (FOA) invites applications for mechanistic research on how age- and sex-related changes in emotion processing develop over the adult life course and how these changes may interact with and inform the understanding of affective dysregulation in adult mental disorders and Alzheimer’s disease.In particular, research is sought that will leverage the already established normative backdrop of generally improved emotion regulation with aging, as well as research that will expand this evidence base.One aim is to clarify the trajectories of change in emotion processing and linked neurobiological and neurobehavioral factors in aging adults who experience mood and anxiety disorders.Equally important aims are to advance understanding of the factors involved in normative maturational shifts in these processes and of sources of individual variation therein, and to clarify how such shifts (or lack thereof) may relate to irregularities in the integrative neural-behavioral mechanisms of affect regulation seen in these adult mental disorders and in Alzheimer’s disease.It is anticipated that such studies may identify novel targets for mental health interventions or prevention efforts, or provide clues as to which available intervention strategies might be optimally applied to normalize emotion dysregulation or to strengthen emotional resilience at particular stages of the adult life cycle.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-17-405.html
Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

Collaborative Aging (in Place) Research Using Technology (CART) (U2C)

Collaborative Aging (in Place) Research Using Technology (CART) (U2C): RFA-AG-16-021 seniorswalking
SOURCE: National Institute on Aging (NIA), National Cancer Institute (NCI), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institute of Neurological Disorders and Stroke (NINDS), National Institute of Nursing Research (NINR), Office of Behavioral and Social Sciences Research (OBSSR)
APPLICATION DEADLINE: Letter of Intent: 12/12/15. Application: 1/12/16 by 5 pm local time of applicant organization.
$ AVAILABLE: Issuing IC and partner components intend to commit an estimated total of $6 million to fund one award over four years.
ELIGIBILITY: * Public/state/private controlled institutions of higher education.
* Hispanic-serving institutions.
* Historically Black Colleges and Universities (HBCUs).
* Tribally Controlled Colleges and Universities (TCCUs).
* Alaska native and native Hawaiian serving institutions.
* Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
* Nonprofits with or without 501(c)(3) IRS status (other than institutions of higher education).
* Small businesses.
* For-profit organizations (other than small businesses).
* State governments.
* County governments.
* City or township governments.
* Special district governments.
* Indian/Native American tribal governments (federally recognized and other than federally recognized).
* Eligible agencies of the federal government.
* U.S. territories or possessions.
* Independent school districts.
* Public housing authorities/Indian housing authorities.
* Native American tribal organizations (other than federally recognized tribal governments).
* Faith-based or community-based organizations.
* Regional organizations.
* Non-domestic (non-U.S.) entities (foreign institutions).
PURPOSE: The purpose of this, Inter-Agency Funding Opportunity Announcement (FOA) is to develop and validate the infrastructure for rapid and effective conduct of future research utilizing technology to facilitate aging in place, with a special emphasis on people from underrepresented groups.
This FOA is designed to support Collaborative Aging (in Place) Research Using Technology (CART) by developing and validating a research infrastructure that has the capacity to integrate data across different projects, incorporates existing technologies, and can accommodate future technologies, designed to assess and intervene across a variety of observational and clinical research studies and settings, and for a range of measures, diseases and populations.
CFDA: 93.399, 93.866, 93.286, 93.853, 93.361
CONTACT: Please see URL for multiple contacts. For more information see http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-16-021.html
From NIH web site, accessed 10/30/15icon
Subject(s) aged/seniors, medical research

BRAIN Initiative: Technology Sharing and Propagation (R03)

RFA-MH-16-725brain
BRAIN Initiative: Technology Sharing and Propagation (R03)
Department of Health and Human Services
National Institutes of Health

Section I. Funding Opportunity Description

Background

The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) InitiativeSM is aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a new dynamic picture of the brain that, for the first time, shows how individual cells and complex neural circuits interact in both time and space. It is expected that the application of these new tools and technologies will ultimately lead to new ways to treat, cure, and even prevent brain disorders.

NIH is one of several federal agencies involved in the BRAIN Initiative. Planning for the NIH component of the BRAIN Initiative is guided by the long-term scientific plan, “BRAIN 2025: A Scientific Vision,” which details seven high-priority research areas and calls for a sustained federal commitment of $4.5 billion over 12 years. This FOA and other BRAIN Initiative FOAs are based on careful consideration by the NIH of the recommendations of the BRAIN 2025 Report, and input from the NIH BRAIN Multi-Council Working Group (MCWG, Roster).  Information about MCWG meetings is available at http://www.braininitiative.nih.gov/index.htm.

In addition to the national BRAIN Initiative, the NIH continues to have a substantial annual investment in neuroscience research. The Institutes and Centers contributing to the NIH BRAIN Initiative support those research efforts through applications received via parent announcements as well as through specific FOAs. Potential applicants to this FOA are strongly encouraged to contact the Scientific/Research Contact if they have any questions about the best FOA for their research.

To promote progress in development of new technologies as well as in theory and data analysis, the BRAIN Initiative encourages collaborations between neurobiologists and researchers with expertise in statistics, physics, mathematics, engineering, and computer science, and NIH welcomes applications from investigators in these disciplines.

Research Objectives

This FOA seeks applications from investigators who can identify new technologies which, if introduced into their laboratory, will enable or promote new research activities that further the aims of the BRAIN initiative as described in the BRAIN 2025 Report.  Injection of these new technologies, whether experimental, theoretical or data analytical, into the applicant’s research program must newly enable experimentation in areas that are relevant to the NIH BRAIN Initiative.  Projects that are successful will result in a publication or other concrete deliverable that will allow the awardee to apply that technology or method in future research, and thus enhance research infrastructure.  This FOA is meant to support work on a particular research project that will illustrate that the technology has been mastered by the receiving laboratory.

NIH also supports dissemination activities between tool developers and the research community in other ways such as the dissemination activities of the BD2K Centers, the collaboration, service, and dissemination activities of the Biomedical Technology Research Resources and various NIH Career Development Awards.  This funding opportunity is distinct in its focus on the dissemination of tools related to the goals of the BRAIN Initiative.

The primary intent of this FOA is to inject technology into a particular laboratory that does not have experience with that technology, with the potential for sustained enhancement of the research conducted by that laboratory.  In some cases, effort may be needed by the developer of the technology to fit the needs of the recipient laboratory.  Such collaborations are welcome since a major purpose of the BRAIN Initiative is to support the development of new tools.  Although the new technology is transferred to a single research group, subsequent dissemination to other groups, performing research related to the aims of the BRAIN initiative, is welcomed.  While it is not required that the awardee have plans to re-distribute their newly gained expertise, groups with the intent and capability to more broadly disseminate their new expertise should briefly describe their plans.

Examples of supported activities include, but are not limited to:

  • Sending a faculty member, graduate student, postdoctoral fellow or technical staff to a company or academic laboratory that has developed a new technology, to collaborate on applying the technology to a problem of interest to the BRAIN initiative.
  • Bringing a member of a company or academic laboratory with a new technology to a research laboratory to establish or train members of the awardee laboratory, in applying the new tool in the context of a specific research project.
  • Establishing a collaboration whereby experts in theory, modeling, computer science, or statistics (TMCS) can introduce newly developed data analytics into the research program of the recipient laboratory. Such collaborations are likely to be most valuable early in the design of an experiment.  As with the tool development examples, the TMCS expert could either host a member of the academic laboratory or could visit that laboratory to disseminate expertise.

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-MH-16-725
Funding Opportunity Title: BRAIN Initiative: Technology Sharing and Propagation (R03)
Opportunity Category: Discretionary
Funding Instrument Type: Grant
Category of Funding Activity: Education
Health
Income Security and Social Services
Category Explanation:
Expected Number of Awards: 10
CFDA Number(s): 93.173 — Research Related to Deafness and Communication Disorders
93.213 — Research and Training in Complementary and Integrative Health
93.242 — Mental Health Research Grants
93.273 — Alcohol Research Programs
93.279 — Drug Abuse and Addiction Research Programs
93.286 — Discovery and Applied Research for Technological Innovations to Improve Human Health
93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders
93.865 — Child Health and Human Development Extramural Research
93.866 — Aging Research
93.867 — Vision Research
Cost Sharing or Matching Requirement: No

Posted Date:Aug 24, 2015

Creation Date:Aug 24, 2015

Original Closing Date for Applications:Jan 6, 2016

  Current Closing Date for Applications:Jan 6, 2016  

Archive Date:Feb 6, 2016

Estimated Total Program Funding:$1,000,000

Award Ceiling:$100,000

Award Floor:

Eligibility

Eligible Applicants:
Special district governments
City or township governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Independent school districts
Public housing authorities/Indian housing authorities
Small businesses
County governments
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Private institutions of higher education
Public and State controlled institutions of higher education
For profit organizations other than small businesses
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative Funding Opportunity Announcement (FOA) is to encourage the transfer of new technologies and new data analysis techniques into a research laboratory. One of the key goals of the BRAIN Initiative is to develop new technologies to improve our understanding of the brain. In order for those technologies to be useful, they need to be broadly disseminated beyond the laboratory or company where they originated. This FOA promotes this goal by providing funds to enable the incorporation of new technologies or data analysis techniques into research programs that further the aims of the BRAIN initiative.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-16-725.html