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Multi-Site Studies for System-Level Implementation of Substance Use Prevention and Treatment Services (R01)

Multi-Site Studies for System-Level Implementation of Substance Use Prevention and Treatment Services (R01)
Department of Health and Human Services
National Institutes of Health

Section I. Funding Opportunity DescriptionRx-Drugs

Implementation science is a growing field. An early area of emphasis for addiction health services researchers was to move beyond training of individual clinicians or service providers as a default implementation strategy, and develop interventions that would achieve broader, sustainable implementation at the organizational level. Some research has begun to look at intra-organizational implementation strategies to further accelerate the implementation of evidence-based practices (or de-implementation of unsupported or harmful practices). However, to date, a major remaining challenge is how to facilitate – in a systematic, scalable, sustainable way – the delivery of evidence-based prevention and treatment services at a system level.

This FOA seeks research projects that will move beyond a focus on how individual clinics or organizations implement a given change, and beyond implementation of interventions that target only a single evidence-based intervention (EBI). The purpose of this FOA is to identify efficacious and effective strategies or techniques for facilitating systems-level change within or across networks of organizations to promote broad use of evidence-based practices for the prevention and/or treatment of substance use disorders or HIV. This FOA seeks applications that can address implementation on a larger, system-level scale that is more analogous to the way policy changes lead to system-level changes in prevention and treatment service delivery. Achieving system-level improvements requires implementation strategies that are sufficiently flexible to address the variation in settings and context across a given system, but that are also generalizable across settings. The multi-site studies supported by this FOA should contribute both practical and conceptual advances.  In practical terms, these studies should provide strategies that can be used to effectively deploy guidelines, practices, and policies across entire systems of care.  In conceptual terms, these studies should also leverage the multi-site platform to test implementation science hypotheses, explore novel methodological approaches, or test new measures or models that can inform future implementation research in this or other health domains.

General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-16-455
Funding Opportunity Title: Multi-Site Studies for System-Level Implementation of Substance Use Prevention and Treatment Services (R01)
Opportunity Category: Discretionary
Opportunity Category Explanation:  
Funding Instrument Type: Grant
Category of Funding Activity: Education
Category Explanation:  
Expected Number of Awards:  
CFDA Number(s): 93.273 — Alcohol Research Programs
93.279 — Drug Abuse and Addiction Research Programs
93.399 — Cancer Control
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Sep 30, 2016
Last Updated Date: Sep 30, 2016
Original Closing Date for Applications: Nov 13, 2020  
Current Closing Date for Applications: Nov 13, 2020  
Archive Date: Dec 14, 2020
Estimated Total Program Funding:  
Award Ceiling: $500,000
Award Floor:


Eligible Applicants: Public housing authorities/Indian housing authorities
City or township governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Independent school districts
Public and State controlled institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
County governments
Private institutions of higher education
Native American tribal governments (Federally recognized)
Special district governments
Small businesses
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Additional Information

Agency Name: National Institutes of Health
Description: As part of the Collaborative Research on Addiction at NIH (CRAN) initiative, NIDA, NIAAA, and NCI join to issue this FOA. The purpose of this FOA is to support the development and testing of interventions, models, and/or frameworks that examine system-level implementation of evidence-based interventions, guidelines, or principles to improve the delivery, uptake, quality, and sustainability of substance use prevention and treatment interventions and services.
Link to Additional Information:
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