Neuroimaging Informatics Tools and Resources Clearinghouse (U24)

Neuroimaging Informatics Tools and Resources Clearinghouse (U24)
Department of Health and Human Services
National Institutes of Health



The Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC) (, originally funded by the NIH Blueprint for Neuroscience Research in 2006, is a dynamic inventory of web-based neuroimaging informatics resources: software, data, and tools accessible via any computer connected to the internet. The purpose of the NITRC project is to promote the enhancement, sharing, adoption, and evolution of neuroimaging informatics tools and resources by providing access, information, and forums for interaction for the user community and the associated developers. The NITRC project was designed to improve scientific research and promote sharing of previously funded research and initiatives and to encourage community interaction and collaboration. NITRC facilitates finding and comparing neuroimaging resources for functional and structural neuroimaging analyses. The goals of NITRC are to catalog and point to standardized information about neuroimaging tools, or resources. In 2011, the scope of NITRC was expanded to provide enhanced services such as virtual computing, and data storage.

The functionality of the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC) has enabled three distinct components to flourish

  • NITRC-R: the NITRC resource for software and tool exchange.
  • NITRC-IR: the NITRC image repository of publicly accessible, anonymized, and curated, clinical neuroimaging data.
  • NITRC-CE: the NITRC compute environment permitting researchers around the globe the ability to do computations on neuroimaging datasets.

NITRC-R has become the major web-based collaborative environment enabling the distribution, enhancement, and adoption of neuroinformatics resources. It currently hosts more than 748 tools and resources in areas such as magnetic resonance imaging (MRI), electroencephalography (EEG),  magnetoencephalography (MEG), multi-modal, positron emission tomography, single photon emission computed tomography (PET / SPECT), computed tomography (CT), clinical neuroinformatics, imaging genomics, optical imaging, and computation neuroscience.

NITRC-IR currently comprises a curated repository of more than 6,000 human subjects’ DICOM and NIfTI-1 images, which are searchable by metadata such as handedness, gender, and grouping. This data is registered on INCF Dataspace and is a Tier 3 resource on the Neuroscience Information Framework (NIF). NITRC-IR is the data repository for the 1000 Functional Connectomes (resting state), the ABIDE study (resting state), CANDIShare (T1 and manual segmentations), ADHD200 (resting state), INDI NKI/Rockland (resting state), PING (structural, diffusion, and resting state), CoRR (test-retest reliability and reproducibility), as well as international studies such as Beijing Enhanced DTI, Beijing Eyes Open Eyes Closed, Beijing Short TR study, Study Forrest rev003 (structural brain scans, physiological measurements, technical confounds), IXI study (normal, healthy subjects MRI scans).

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-EB-16-002
Funding Opportunity Title: Neuroimaging Informatics Tools and Resources Clearinghouse (U24)
Opportunity Category: Discretionary
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Education
Income Security and Social Services
Category Explanation:
Expected Number of Awards: 1
CFDA Number(s): 93.113 — Environmental Health
93.213 — Research and Training in Complementary and Integrative Health
93.242 — Mental Health Research Grants
93.273 — Alcohol Research Programs
93.279 — Drug Abuse and Addiction Research Programs
93.286 — Discovery and Applied Research for Technological Innovations to Improve Human Health
93.361 — Nursing Research
93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders
93.865 — Child Health and Human Development Extramural Research
93.866 — Aging Research
93.867 — Vision Research
Cost Sharing or Matching Requirement: No
Posted Date: Jan 13, 2016
Creation Date: Jan 13, 2016
Original Closing Date for Applications: Mar 15, 2016  
Current Closing Date for Applications: Mar 15, 2016  
Archive Date: Apr 15, 2016
Estimated Total Program Funding: $600,000
Award Ceiling:
Award Floor:


Eligible Applicants:
Native American tribal governments (Federally recognized)
Public and State controlled institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
Special district governments
State governments
County governments
Private institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Additional Information on Eligibility: See full announcement for complete details.

Additional Information

Agency Name: National Institutes of Health
Description: The purpose of this FOA is to support the Neuroimaging Informatics Tools and Resources Clearinghouse and to enable collaborative research in neuroimaging informatics
Link to Additional Information:
Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

eRA Service Desk Monday to Friday 7 am to 8 pm ET Phone 1-866-504-9552
Grants Info


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