Understanding Barriers and Facilitators to Type 1 Diabetes Management in Adults (DP3)


Understanding Barriers and Facilitators to Type 1 Diabetes
Management in Adults (DP3)

Department of Health and Human Services
National Institutes of Health

Section I. Funding Opportunity DescriptionDiabetes_Management_1

Diabetes management requires a complex regimen of blood glucose monitoring, medication dosing, and adjustments in diet and physical activity in order to achieve tight glucose control while avoiding hypoglycemia. Most of the observational and intervention research on diabetes self-management in type 1 diabetes has been conducted in youth and young adults. The data that exist about diabetes self-management in adults is often in mixed samples of individuals with type 2 and type 1 diabetes without adequate power to detect unique factors related to managing type 1 diabetes. Without a better understanding of the barriers and facilitators for good self-management in adults, it is difficult to develop treatment approaches that are tailored to specific risk factors or high risk groups.

For the purposes of this FOA, research should focus on one or more adult age ranges; young working age adults (25-44), older working age adults (45-64), and/or older adults (65 and older). Researchers can include any age range of adults but the research questions should be appropriate to the hypothesized factors affecting diabetes management in those age groups. For example, in working age adults, understanding specific life issues, such as building and caring for a family and establishing and maintaining a career and their effects on diabetes self-management would be appropriate. In older adults the focus might be on issues of managing diabetes in the context of age and diabetes-related changes in functioning (e.g., onset of cardiovascular disease, fractures and musculoskeletal disorders, vision loss, end-stage renal disease, painful neuropathy, cognitive impairment, and hearing loss) or changes in living situation such as assisted living or nursing home facilities.

This FOA will support observational and mixed methods (quantitative and qualitative) research designed to elucidate the factors (e.g., medical, social, economic, environmental, behavioral, or psychological) that influence diabetes self-management and diabetes outcomes (e.g., HbA1c, hypoglycemia, DKA), in a positive or harmful way, in adults.  Longitudinal research is strongly encouraged and cross sectional research is discouraged.

The targets of the research might include understanding:

  • Helpful and not helpful types of diabetes support from the social and familial networks, including spouses or partners, children, friends and coworkers;
  • Health care team and health care system factors that influence self-management, such as provider-patient communication, models of care delivery, access, and reimbursement schemes;
  • Risks related to life stage or context, such as pregnancy, workplace constraints or support, co-morbid health conditions/complications, and socioeconomic status;
  • Use of new or existing technologies, including insulin pumps, blood glucose monitors, continuous glucose monitoring systems, and web or mobile health resources; and
  • Individual factors and their influence on adherence and self-management, such as health literacy or numeracy, health beliefs such as over or under-prediction of risk, and psychological co-morbidities such as depression and anxiety.

The goal of the research conducted should be to identify factors associated with poor diabetes outcomes including challenges to diabetes self-management and reduced quality of life. The research supported by this FOA is intended to identify possible targets for future intervention research.

Given the likely challenges in recruiting large samples of adults with type 1 diabetes, applicants are encouraged to capitalize on existing resources such as patient registries, electronic health records, patient networks, and advocacy organizations to facilitate recruitment.

If it is possible for NIDDK to fund more than one application in response to this FOA, exchange of ideas and collaboration between funded investigators will be encouraged though yearly investigator meetings.

Research in response to this initiative should be for human studies only.

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-DK-16-002
Funding Opportunity Title: Understanding Barriers and Facilitators to Type 1 Diabetes Management in Adults (DP3)
Opportunity Category: Discretionary
Funding Instrument Type: Grant
Category of Funding Activity: Food and Nutrition
Category Explanation:
Expected Number of Awards: 2
CFDA Number(s): 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research
Cost Sharing or Matching Requirement: No
Posted Date: Dec 8, 2015
Creation Date: Dec 8, 2015
Original Closing Date for Applications: Jun 22, 2016  
Current Closing Date for Applications: Jun 22, 2016  
Archive Date: Jul 23, 2016
Estimated Total Program Funding: $5,000,000
Award Ceiling: $2,500,000
Award Floor:


Eligible Applicants:
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
State governments
Native American tribal governments (Federally recognized)
Private institutions of higher education
Public and State controlled institutions of higher education
Independent school districts
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
City or township governments
Special district governments
County governments
Public housing authorities/Indian housing authorities
For profit organizations other than small businesses
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Additional Information

Agency Name: National Institutes of Health
Description: The goal of this Funding Opportunity Announcement (FOA) is to support research that will identify barriers and facilitators to good diabetes self-management in adults with type 1 diabetes. The results from this research should inform future intervention research in adults with type 1 diabetes.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-16-002.html
Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster


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